What Is Hydromorphone?
Hydromorphone is the generic version of brand name prescription Opioids, Dilaudid® and Exalgo®. It is derived from Morphine found in the Opium poppy plant. However, the byproduct is more than twice as potent; 30 mg of Morphine taken in pill form is equivalent to approximately 7.5 mg of Hydromorphone. The medication belongs to a category of Opiate analgesics that can relieve pain yet have potentially deadly side effects in the central nervous system (such as reduced breathing and heart rates), especially when taken in larger doses. For this reason, prescription Opioids are involved in 46 overdose deaths every day in the U.S.
Categorized as a Schedule II substance with high dependence and abuse potential, physicians today are more careful about writing Hydromorphone prescriptions. The U.S. Opioid prescribing rate has fallen from 2012 to 2017, hitting its lowest point in more than a decade at 58.7 prescriptions per 100 people. As such, the illicit supply of the medication is usually secured by doctor-shopping (visiting multiple doctors for prescriptions), forged prescriptions, armed robberies, heft of pharmacies and nursing homes, smuggling from other countries, and online via the dark web. In 2013, the Drug Enforcement Administration reported the street price of 4 mg of Dilaudid can cost as much as $100 per pill in some areas of the country.
Common Street Names for Hydromorphone include:
D
Dillies
Footballs
Juice
Smack
Effects of Hydromorphone
Hydromorphone is typically prescribed as a pill taken every 4 to 6 hours for the management of round-the-clock pain over a long period of time. Because of their relative strength in comparison to other prescription pain relievers, Hydromorphone is generally reserved for severe pain treatments, and not for patients with “as needed” pain medication or for recovery from surgery. It is also used for those who have become so tolerant to the effects of weaker Opioids that they are no longer providing the desired effects.
No matter how they enter the body, all Opioids travel to the brain and bind to specific receptors. They also interact with Opioid receptors in the spinal cord, gastrointestinal tract, and other parts of the body. In up to 30 minutes (when taken by mouth in pill form), these interactions reduce the perception of pain and produce sensations of euphoria. However, the euphoric sensations generally only occur in non-Opioid tolerant individuals, those who have not been taking the medication for very long, or those who have recently increased their dose. Its pain-relieving properties usually last 5 or more hours.
Other effects of Hydromorphone include:
Drowsiness
Mental confusion
Nausea
Constipation
Stomach pain
Flushed skin
Heavy sweating
Itching
Hydromorphone Addiction
When taken for a prolonged period of time, Opioid medication may become habit-forming. Anyone can become physically and mentally dependent on Opioids due to the way they interact with the brain’s reward response system. Opioids trigger the release of dopamine (people feel this as a warm rush or sensation of well-being). Repeated use desensitizes the body to their effects, and, in time, the body becomes reliant on Opioids to function normally. This can lead to the establishment of an addiction–not everyone who uses or misuses their prescription will become addicted.
An Opioid addiction (also known as an Opioid Use Disorder) involves uncontrollable drug-seeking behavior that persists despite negative consequences. An individual suffering from addiction is not able to stop even though they are typically aware of the damage they’re doing to their own life, as well as the lives around them. Some people may take too much and experience an overdose.






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